Mit dieser Elf startet der FC Schalke in die Saison
| Tor | ||
| 1 | Fährmann, Ralf | |
| 23 | Rönnow, Frederik | |
| 34 | Michael Langer | |
| Abwehr | ||
| 2 | Ludewig, Kilian | |
| 3 | Mendyl, Hamza | |
| 5 | Nastasic, Matija | |
| 13 | William (seit 01/2021) | |
| 17 | Stambouli, Benjamin | |
| 20 | Kolasinac, Sead (seit 01/2021) | |
| 24 | Oczipka, Bastian | |
| 26 | Sané, Salif | |
| 30 | Mustafi, Shkodran (seit 01/2021) | |
| 31 | Becker, Timo | |
| 33 | Thiaw, Malick | |
| Mittelfeld | ||
| 6 | Mascarell, Omar | |
| 8 | Serdar, Suat | |
| 10 | Bentaleb, Nabil | |
| 16 | Boujellab, Nassim | |
| 25 | Harit, Amine | |
| 28 | Schöpf, Alessandro | |
| 37 | Mercan, Levan | |
| 40 | Bozdogan, Can | |
| Angriff | ||
| 7 | Uth, Mark | |
| 14 | Matondo, Rabbi | |
| 15 | Kutucu, Ahmed (bis 12/2020) | |
| 18 | Paciencia, Goncalo | |
| 21 | Huntelaar, Klaas-Jan (seit 01/2021) | |
| 22 | Skrzybski, Steven | |
| 43 | Hoppe, Matthew |